NIHR Alder Hey Clinical Research Facility

NIHR Alder Hey Clinical Research Facility

A patient tours the CRF before taking part in a research studyOur bespoke Clinical Research Facility (CRF) provides a state-of-the-art and dedicated environment for patients, healthcare professionals, and academic and commercial partners to deliver leading edge research, placing Alder Hey at the forefront of improving the health and well-being of children and young people.

The facility staffed by an expert team of paediatric research nurses, along with doctors including those with specialist clinical pharmacology knowledge, clinical trial pharmacists, research physiotherapist, research play specialist, clinical trial administrators and clinical trial coordinators and quality assurance officer, enables Alder Hey to safely deliver, high intensity complex research studies of new medications and interventions, including those requiring inpatient, overnight care. Fully equipped and purpose built, the CRF significantly increases the capacity of Alder Hey to carry out essential paediatric research, including experimental medicine and early phase studies. The attractive, child friendly environment of the facility enhances the experience of all those involved in research studies and helps encourage greater participation. It is the first ever facility of its kind in Merseyside and Cheshire.

Studies conducted on the CRF are done so to strict Good Clinical Practice (GCP) standards. Sitting in the heart of Alder Hey Children’s Hospital, the facility is located close to critical care, medical inpatient facilities and clinical support services. This means Alder Hey is providing the highest, possible quality environment for safety, clinical and research governance. The CRF environment has been designed with the involvement of children and young people to ensure that their needs are met within the space available. This includes spaces for social interaction as well as the possibility for isolation and privacy in either the daycase area or individual rooms.
Research taking place within the CRF covers all specialties within the hospital, however priority areas include musculoskeletal disease, infection with a growing focus on oncology and neurosciences.  Studies include investigating diseases and developing novel therapies, medicines and drugs. This includes experimental and early phase studies to establish the best route of medicine administration and correct dosages for children and young people.

The CRF is supported by high specification equipment and platforms in Radiology and Pathology with expert research staff based in each of these departments. The CRF team also provides an outreach role, working with clinical teams in paediatric Intensive Care, Oncology, A&E and the Neonatal Intensive Care Unit at Liverpool Women’s Hospital.  In addition we work in collaboration with the team at the Royal Liverpool and Broadgreen University Hospital NHS Trust Clinical Research Unit (RLBUHT CRU) to offer a “life-course” platform for research with the city of Liverpool and across the region.
In April 2017, the CRF received a substantial grant from the National Institute of Health Research (NIHR). £2m will provide five years of funding, enabling Alder Hey to further pioneer research to benefit children and young people.

Importantly the CRF works in partnership with the commercial sector, including pharmaceutical companies, small / medium enterprises and technology/device manufacturers as well as the academic sector, including the Faculties of Health & Life Sciences and Science & Engineering at University of Liverpool;  Schools of Pharmacy at Liverpool John Moores University and University of Central Lancashire to design and deliver research studies . 

For more details, please contact:
Gaurika Kapoor, NIHR Alder Hey CRF Operations Manager
gaurika.kapoor@alderhey.nhs.uk

Meet the team

Gaurika Kapoor - CRF Operational Manager

Teresa Moorcroft – Research Nurse Manager

Tim Henderson – Research Nurse

Hannah Leyland – Research Nurse

Leanne Minards – Research Nurse

Jackie Lyall – Research Nurse

Fiona Wilson – Research Nurse

Jackie Glover – Research Play Specialist

Dr Dan Hawcutt – CRF clinical lead

Udeme Ohia – Clinical trials Pharmacist

Nadia Ismail – Data Assistant

Aiste Adomaviciene – Neuromuscular trial coordinator

Emma McDonough - PMRU Research Coodinator

Rebecca Hamilton-Cook -  CRF Industry Manager
 

Clinical Research Facility Service Evaluation


Alder Hey Children's Charity
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